Web13 apr. 2024 · Stoy, N. Involvement of Interleukin-1 Receptor-Associated Kinase 4 and Interferon Regulatory Factor 5 in the Immunopathogenesis of SARS-CoV-2 Infection: Implications for the Treatment of COVID-19. Front. Immun. 2024, 12, 638446, DOI: 10.3389/fimmu.2024.638446 WebKaposi’s Sarcoma-Associated Herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathway J. Virol. 2009 83 (13): 6739-6747
I型干扰素(IFN-1)信号通路调控对HIV感染的启示 VS亮点推荐
Web7 sep. 2024 · A new water-soluble heteropolysaccharide with a molecular weight of 15 kDa was isolated from the fruiting bodies of Boletus reticulatus Schaeff. Structural characterization results revealed that B. reticulatus Schaeff polysaccharide (BRS-X) had a backbone of 1,6-linked α - D galactose and 1,2,6-linked α >-D-galactose which … WebTfR1 is up-regulated by the hypoxia-inducible factor (HIF-1), we investigated the effect of inflammatory and anti-inflamma-torysignalsonHIF-1 … pod propulsion system
单细胞应用|单细胞测序揭示HIF-1α的抑制释放NK细胞活性 - 知乎
WebInterestingly, our results show that α-casein upregulates gene transcripts associated with interferon/STAT1 signaling and downregulates genes ... ATG16L, BNIP3, BNIP3L, HIF-1α and NFκB. In addition, pharmacological activation of HIF-1α drives Cav-1 degradation, while pharmacological inactivation of HIF-1 prevents the downregulation ... Web20 okt. 2024 · Verucopeptin decreases the HIF-1 protein level in a dose-dependent manner. But it has no effects on c-Raf in HT1080 cells. However, the known hsp90 inhibitor Tanespimycin inhibits both HIF-1 and c-Raf expression in cells. In BALB/c nude mice by subcutaneous injection of SGC7901/VCR cells model. Webhif-1α可能是ifn-γ与tnf-α协同引起肠上皮屏障功能损害的重要介质。 2.hif-1α抑制剂寡霉素及yc-1均能减轻ifn-γ与tnf-α协同作用引起的肠上皮屏障功能损害、tj蛋白zo-1及occludin形态 … pod print on demand software