Cdh5 cre ert2
Web017968 B6;129-Tg(Cdh5-cre)1Spe/J These VEC-cre transgenic mice express Cre recombinase under the control of a Cdh5 promoter with greater efficiency than other … WebThe Cdh5(PAC)-CreERT2 mouse exhibits tissue-specific expression of an inducible Cre-ERT2 fusion protein, enabling tamoxifen-induced Cre recombinase activity in vascular …
Cdh5 cre ert2
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WebMay 17, 2024 · The tamoxifen-responsive conditional Cdh5-CreERT2 is commonly used for endothelial cell specific conditional deletion of loxP … Web006137 B6.FVB-Tg(Cdh5-cre)7Mlia/J Cre expression in these transgenic mice can be seen in the embryo and in adult endothelium of developing and quiescent vessels, as well as …
WebTg(Cdh5-cre/ERT2)1Rha transgene insertion 1, Ralf H Adams MGI:3848982 Filter references by: Author Journal Year Data Reference Type 0 reference(s) match after applying filter(s) WebMay 17, 2024 · The tamoxifen-responsive conditional Cdh5-CreERT2 is commonly used for endothelial cell specific conditional deletion of loxP-flanked gene sequences. To address …
WebThe transgene consists of a tamoxifen-inducible cre recombinase driven by the 2.3-kb mouse Col1a1, collagen, type I, alpha 1, promoter. The transgene insert contains a fusion product involving cre recombinase and a mutant form of the mouse estrogen receptor ligand binding domain. WebOct 11, 2024 · The 852 area code covers the Hong Kong Island, Kowloon and the New Territories. The 852 area code is one of the most densely populated areas in the world. …
WebAs proof-of-principle, we have crossed these mice with Cdh5-Cre ERT2 mice to generate CD63 emGFP+ vasculature. Using these mice, we show that developing vasculature is …
WebWe examined the use of ERT2-iCre-ERT2 (Cre2ERT2), a tamoxifen-regulated form of Cre that has been described to have a background activity lower than that of other tamoxifen-regulated Cre constructs, for establishing performant conditional deleter mouse lines. Cre2ERT2 was inserted by homologous recombination into the Rosa26 locus. crime clearance rates in irvine californiaWebApr 11, 2024 · The conditional S1pr2 knockout mice ( S1pr2flox/flox) and S1pr2 gain-of-function mice ( S1pr2Tg/+) were generated as previously reported. 12 Cadherin 5 (Cdh5, also known as vascular endothelial cadherin) is localized at the EC junction and specifically expressed in ECs. 13 We used a tamoxifen-inducible Cdh5 promoter-driven Cre line … crime clock 2012WebNov 14, 2024 · Here, we demonstrate that a murine EC lineage-tracing model (Cdh5-CreERT2:ZSGreenl/s/lmice) can be used to isolate EC-derived extracellular vesicles (EC-EVs). budget national airlinesWebRecombinase (cre) Nomenclature; References; Clone Collections; DNA Mapping Panels; More Resources. More Resources Index; Research Community E-mail Lists; Online Books; ... (Ccr2-cre/ERT2)12Kuan transgene insertion, Chia-Yi Kuan Driver: Ccr2 Type: Transgenic (Inducible, Recombinase) Inducer: tamoxifen Synonym: CCR2-CreER(T2) ... budget nath edhWebIntegration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. The TGFβ type II receptor plays a critical role in the endothelial cells during cardiac development. crime clearance rates by cityWebJun 18, 2024 · Treatment of eNOS flox/flox Cdh5-Cre/ERT2 pos/neg with tamoxifen induces an EC-specific Cre-mediated DNA recombination leading to excision of exon 2 in the Nos3 genomic locus to obtain EC eNOS KO (eNOS flox/flox Cdh5-Cre/ERT2 pos) or their littermate WT (eNOS flox/flox Cdh5-Cre/ERT2 neg) controls (Table 1). crime clock 2016WebAug 11, 2024 · EndMT was investigated using lineage tracing with transgenic Cdh5-Cre-ERT2; Rosa26R-stop-YFP mice in two established models of fibrosis: cardiac ischaemic injury and kidney ureteric occlusion. crime cleaner game